Mitragynine Toxicity: The Silent Threat Behind the “Natural High” Craze
Fact Information Compound Mitragynine Source Leaves of Mitragyna speciosa (Kratom tree) Native Region Southeast Asia (Thailand, Malaysia, Indonesia, Borneo) Mechanism Partial μ-opioid receptor agonist Common Uses Pain relief, energy boost, euphoria, opioid withdrawal substitute Toxic Dose No universally accepted threshold; fatal levels range from 250–1060 ng/mL Administration Oral (tea, capsules, powder), smoked, chewed Legal Status…